Dormant, experimental cells begin to awaken inside their human hosts, turning them into creatures called 'Amazons'. Two Amazons- Jin Takayama and Haruka Mizusawa- transform into Kamen Riders Amazon Alpha and Amazon Omega, aiming to exterminate the growing threat.

• Tom Fujita
• Masashi Taniguchi
• Ayu Higashi
• Ryota Kobayashi
• Mitsutoshi Shundo
• Kanon Miyahara
• Kazuya Tanabe
• Takako Katou